Search results for "Ion guide"
showing 10 items of 25 documents
A mismatch between athlete practice and current sports nutrition guidelines among elite female and male middle- and long-distance athletes
2017
Contemporary nutrition guidelines promote a variety of periodized and time-sensitive recommendations, but current information regarding the knowledge and practice of these strategies among world-class athletes is limited. The aim of this study was to investigate this theme by implementing a questionnaire on dietary periodization practices in national/international level female (n = 27) and male (n = 21) middle- and long-distance runners/race-walkers. The questionnaire aimed to gain information on between and within-day dietary choices, as well as timing of pre- and posttraining meals and practices of training with low or high carbohydrate (CHO) availability. Data are shown as percentage (%)…
Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers
2011
Abstract Purpose: To facilitate development of innovative immunotherapy approaches, especially for treatment concepts exploiting the potential benefits of personalized therapy, there is a need to develop and validate tools to identify patients who can benefit from immunotherapy. Despite substantial effort, we do not yet know which parameters of antitumor immunity to measure and which assays are optimal for those measurements. Experimental Design: The iSBTc-SITC (International Society for Biological Therapy of Cancer-Society for Immunotherapy of Cancer), FDA (Food and Drug Administration), and NCI (National Cancer Institute) partnered to address these issues for immunotherapy of cancer. Here…
Design, construction and cooling system performance of a prototype cryogenic stopping cell for the Super-FRS at FAIR
2015
A cryogenic stopping cell for stopping energetic radioactive ions and extracting them as a low energy beam was developed. This first ever cryogenically operated stopping cell serves as prototype device for the Low-Energy Branch of the Super-FRS at FAIR. The cell has a stopping volume that is 1 m long and 25 cm in diameter. Ions are guided by a DC field along the length of the stopping cell and by a combined RF and DC fields provided by an RE carpet at the exit-hole side. The ultra-high purity of the stopping gas required for optimum ion survival is reached by cryogenic operation. The design considerations and construction of the cryogenic stopping cell, as well as some performance character…
Characterization of a cryogenic ion guide at IGISOL
2012
A small volume cryogenic ion guide has been characterized at the IGISOL facility, Jyvaskyla, as a prototype to verify whether there are any major obstacles to the use of high-density cryogenic helium gas for the stopping and extraction of high-energy ions from a large volume cryogenic ion catcher. The expected temperature scaling of the mass flow through the ion guide has been confirmed, showing that for the same helium density, the differential pumping requirements are less stringent for cryogenic operation. At 90 K a clear reduction in the mass-analyzed impurities is achieved, although lower temperatures are required to freeze out oxygen and nitrogen. This is supported by the reduction in…
Production of neutron deficient rare isotope beams at IGISOL; on-line and off-line studies
2004
This article reports on recent on-line yield measurements employing the light-ion and heavy-ion reaction-based ion guide systems and new results on a-recoil ion transport properties in ion guides with and without electric fields. In addition, the presently used ion guide designs for fusion evaporation reactions are introduced. The present study investigated different schemes for ion extraction from the gas cell. The addition of an extra ring electrode between the traditional skimmer electrode and the exit hole led to transmission independent of the primary beam intensity as opposed to strong intensity dependence observed earlier with the plain skimmer only. Furthermore, the mass resolving p…
A setup to develop novel Chemical Isobaric SEparation (CISE)
2020
Abstract Gas catchers are widely used to thermalize nuclear reaction products and subsequently extract them for precision measurements. However, impurities in the inert stopping gas can chemically react with the ions and thus influence the extraction efficiency. So far, chemical reactions in the gas-catcher have not been investigated in detail. Therefore, we are currently building a new setup to develop Chemical Isobaric SEparation (CISE) with the aim to understand the chemistry inside the gas-catcher and to explore its potential as a new technique for separation of isobars. In this paper, we give a short description of the setup together with the ion transportation studies performed via io…
Resonance laser ionization developments for IGISOL-4
2012
The work presented in this thesis concentrates on the development of the FURIOS laser ion source towards e cient and selective production of low energy radioactive ion beams. This includes design and development of the ion guide and hot cavity catcher systems for laser ion source use, and the development of in-source and in-jet laser spectroscopy techniques. The work has been carried out at the IGISOL facility in the Accelerator laboratory of the University of Jyväskylä. The FURIOS facility was upgraded and developed during the move to the IGISOL-4 facility. The laser transport was greatly improved in order to allow a large fraction of the initial laser intensity to be transported into the …
The development and status of the IGISOL technique
1997
Abstract The development of the IGISOL technique since its earliest beginnings at the University of Jyvaskyla in the early '80s is reviewed. The processes involved in ion survival in the ion guide are discussed. The design and performance of ion guides for different types of reactions is summarised. The mass-separated beam quality for different skimmer systems is compared.
Off-line studies of the laser ionization of yttrium at the IGISOL facility
2007
A laser ion source is under development at the IGISOL facility, Jyvaskyla, in order to address deficiencies in the ion guide technique. The key elements of interest are those of a refractory nature, whose isotopes and isomers are widely studied using both laser spectroscopic and high precision mass measurement techniques. Yttrium has been the first element of choice for the new laser ion source. In this work we present a new coupled dye-Ti:Sapphire laser scheme and give a detailed discussion of the results obtained from laser ionization of yttrium atoms produced in an ion guide via joule heating of a filament. The importance of not only gas purity, but indeed the baseline vacuum pressure in…
A linear radiofrequency ion trap for accumulation, bunching, and emittance improvement of radioactive ion beams
2000
An ion beam cooler and buncher has been developed for the manipulation of radioactive ion beams. The gas-filled linear radiofrequency ion trap system is installed at the Penning trap mass spectrometer ISOLTRAP at ISOLDE/CERN. Its purpose is toaccumulate the 60-keV continuous ISOLDE ion beam with high efficiency and to convert it into low-energy low-emittance ion pulses. The efficiency was found to exceed 10\,\% in agreement with simulations. A more than 10-fold reduction of the ISOLDE beam emittance can be achieved. The system has been used successfully for first on-line experiments. Its principle, setup and performance will be discussed. An ion beam cooler and buncher has been developed fo…